Ajụjụ ndị a na-ajụkarị na Akụrụngwa
Azịza maka ndị agha
Tupu edebanye aha gị n'ụzọ zuru ezu dị ka onye so na RISE UP, otu ụlọ ọgwụ ga-enyocha akụkọ ahụike na ahụike gị iji hụ na ị nwere ike isonye. Hụ Ịkpebi Ịdebanye aha ka ị nweta echiche ka mma ma ọ bụrụ na nnwale ahụ dị gị mma.
Nkeji nke 2 nke ọmụmụ ihe RISE UP zuru ụwa ọnụ gosiri mmụba dị ịrịba ama na nzaghachi hemoglobin karịrị izu iri na abụọ na mitapivat ma e jiri ya tụnyere placebo.
Ngụkọta nke ndị ọrịa 79 ka edebanyere aha na ọmụmụ ihe nkeji nke abụọ RISE UP zuru ụwa ọnụ. Ebe ndị ọrịa 27 natara placebo, enwere ndị ọrịa 52 natara mitapivat.
Mitapivat kwalitere ihe nrịbama nke hemolysis na erythropoiesis ma e jiri ya tụnyere placebo. Ihe nrịbama maka hemolysis ga-agwa gị ka mkpụrụ ndụ ọbara uhie gị si dị mma, ihe nrịbama maka erythropoiesis na-agwakwa gị ọsọ nke a na-emepụta mkpụrụ ndụ ọbara uhie na mkpụrụ ndụ ọbara ndị ọzọ.
Mitapivat gosikwara mbelata ihe karịrị 50 %na nsogbu mgbu sickle cell (SCPC) ma e jiri ya tụnyere placebo.
Ee, otu ndị dọkịta ejibu na nkeji abụọ ka a ga-eji maka nkeji 3, yana ụfọdụ ndị dọkịta ndị ọzọ.
Ọmụmụ ihe Mitapivat na-ga kemgbe Maachị 2014.
Ihe karịrị ndị ọrịa 700, gụnyere ndị ọrụ afọ ofufo ahụike, ka ejiri mitapivat gwọọ ọrịa dị iche iche.
Ọmụmụ ihe Mitapivat na-ga ihe karịrị afọ 5.
Mitapivat dị ka ọgwụgwọ na-agbanwe ọrịa nwere ike ime ka ọrịa gị dịkwuo mma, mana ọ gaghị agbanwe DNA gị.
N'ime nkeji nke 3 nke ọmụmụ ihe, maka ndị ọrịa atọ ọ bụla na-esonye, abụọ ga-anọ na mitapivat na otu ga-anọ na placebo.
Otú ọ dị, enwere oge ọmụmụ ihe ndọtị a na-ekpuchighị mkpuchi nke afọ 4 di nhọrọ nke onye ọ bụla na-enweta mitapivat.
Ebumnuche nke nkeji ọmụmụ ihe a nke 3 bụ iji chọpụta ma mitapivat ọ dị mma ma dị irè.
Ọ nweghị ndị ọrịa mitapivat ma ọ bụ placebo kwụsịrị ọgwụgwọ n'ihi mmetụta dị n'oge ọmụmụ ihe nke 2.
N'ime ọmụmụ ihe niile nke mitapivat, mmetụta ndị a na-ahụ na 10% ma ọ bụ karịa ndị ọrịa gụnyere isi ọwụwa, ike ọgwụgwụ, ọgbụgbọ, mgbu nkwonkwo, na COVID-19.
Mitapivat nwere ike imetụta ụzọ ọgwụ ndị ọzọ si arụ ọrụ, yana ọgwụ ndị ọzọ nwere ike imetụta ụzọ mitapivat si arụ ọrụ. Ịṅụ mitapivat na ọgwụ ndị ọzọ nwekwara ike ịkpata mmetụta.
Gwa dọkịta gị gbasara ọgwụ ị na-aṅụ ugbu a (gụnyere ọgwụ ndenye, ọgwụ ndị a na-ere ahịa na ihe mgbakwunye, na ngwaahịa ọ bụla nwere mkpụrụ osisi grepu). Dọkịta ọmụmụ ihe gị ga-eme ka ị mata ọgwụ ndị dị mma ị ga-aga n'ihu na-aṅụ mgbe ị nọ na mitapivat.
Ọ bụrụ na edebanye aha, isonye na ọmụmụ ihe nke 3 bụ otu afọ.
Ee, anyị ga-amasịkwa gị isonye na mmegharị ahụ. Debanye aha ebe a.
Naìjíríyà
- The University of Nigeria Teaching HospiatalOzi ịkpọtụrụ: 2348888888888
- Lagos University Teaching Hospital HaematologyOzi ịkpọtụrụ: 2348023535659
- University of Abuja Teaching HospitalOzi ịkpọtụrụ: 2348130610603
- Barau Dikko Teaching Hospital (BDTH), KadunaOzi ịkpọtụrụ: 2348037051283
- National Hospital AbujaOzi ịkpọtụrụ: 2348180341795
- University of Calabar Teaching HospitalOzi ịkpọtụrụ: 2348036742377
- The University of Nigeria Teaching HospiatalOzi ịkpọtụrụ: 2348888888888
- Lagos University Teaching Hospital HaematologyOzi ịkpọtụrụ: 2348023535659
- University of Abuja Teaching HospitalOzi ịkpọtụrụ: 2348130610603
- Barau Dikko Teaching Hospital (BDTH), KadunaOzi ịkpọtụrụ: 2348037051283
- National Hospital AbujaOzi ịkpọtụrụ: 2348180341795
- University of Calabar Teaching HospitalOzi ịkpọtụrụ: 2348036742377
- The University of Nigeria Teaching HospiatalOzi ịkpọtụrụ: 2348888888888
- Lagos University Teaching Hospital HaematologyOzi ịkpọtụrụ: 2348023535659
- University of Abuja Teaching HospitalOzi ịkpọtụrụ: 2348130610603
- Barau Dikko Teaching Hospital (BDTH), KadunaOzi ịkpọtụrụ: 2348037051283
- National Hospital AbujaOzi ịkpọtụrụ: 2348180341795
- University of Calabar Teaching HospitalOzi ịkpọtụrụ: 2348036742377
- The University of Nigeria Teaching HospiatalOzi ịkpọtụrụ: 2348888888888
- Lagos University Teaching Hospital HaematologyOzi ịkpọtụrụ: 2348023535659
- University of Abuja Teaching HospitalOzi ịkpọtụrụ: 2348130610603
- Barau Dikko Teaching Hospital (BDTH), KadunaOzi ịkpọtụrụ: 2348037051283
- National Hospital AbujaOzi ịkpọtụrụ: 2348180341795
- University of Calabar Teaching HospitalOzi ịkpọtụrụ: 2348036742377
Placebo bụ ọgwụ dị ka ọgwụ ọmụmụ ihe mana enweghị ọgwụ ọ bụla dị na ya. Placebo na-enyegasị ụzọ iji tụnyere nsonaazụ nke ọgwụ nyocha mepụtara. "Okpukpu abụọ" pụtara na gị na dọkịta gị agaghị ama ma ị na-aṅụ placebo ma ọ bụ ọgwụ ọmụmụ ihe, ka ị ghara imetụta nsonaazụ ma ọ bụ nyocha.
N'ime ọmụmụ ihe ahụ, a ga-edobe aha gị na ozi ahụike gị niile nke nzuzo. A ga-ekenye onye ọ bụla so na ọmụmụ ihe, ihe nchọpụta pụrụ iche. Ndekọ na data anakọtara n'oge ọmụmụ ihe agaghị enwe aha gị ma ọ bụ ozi njirimara gị, kama ihe njirimara pụrụ iche.
Ị nwere ihe ndị ọzọ na-eme na ndụ gị, na ịlụso ọrịa sickle cell ọgụ kwa ụbọchị bụ nnukwu ihe ịma aka. Ọ bụrụ na ịchọrọ enyemaka n'oge ọmụmụ ihe, nkwado nwere ike ịdị maka:
- Ndị nlekọta
- Nlekọta ụmụaka
- Njem
- Ụgbọ njem
- Nkwụ ụgwọ
- Ndị nọọsụ maka nleta anya
- Nleta mebere
Ọrụ ndị a dị n'elu dabere na iwu mpaghara na nke mba. Biko kpọtụrụ onye nyocha mpaghara gị iji gosi ọrụ ndị dị na mpaghara gị. Ozi ndị ọzọ gbasara nkwado ga-adị na webụsaịtị ndebanye aha gị kpọmkwem.
Otu n'ime nnukwu mkpali m (ịlụ ọgụ) bụ ndị nọ n'ime obodo sickle cell.
Onyeagha orịa Sickle Cell