Deciding to Enroll in the Sickle Cell Clinical Trial

What It Takes To Join Rise Up

Teonna, Sickle Cell Warrior

Sickle Cell Warrior

Reasons Rise Up Might Be a Good Fit

Eligibility criteria:

  • You're 16 years of age or older
  • You're diagnosed with sickle cell
  • If you or your partner are capable of becoming pregnant, you must agree to use 2 forms of contraception
  • You've had at least 2 but no more than 10 pain crises in the past year
    • Defined as pain requiring medical attention and treatment caused by acute chest syndrome, sustained erection, or red blood cell blockages in the liver, spleen, or elsewhere in the body
  • You have a hemoglobin level between 5.5 and 10.5 g/dL
  • If you are taking hydroxyurea, your hydroxyurea dose must stay the same for at least 90 days before starting this study drug
DeMitrious, Sickle Cell Warrior

Sickle Cell Warrior

Reasons Rise Up Might Not Be a Good Fit

  • If you're pregnant or breastfeeding
  • If you're receiving regularly scheduled transfusions
  • If you have any hepatobiliary disorders, including liver or gallbladder disease
  • If you have severe kidney disease
  • If you've undergone gene therapy or had a prior bone marrow or stem cell transplant
  • If you're currently receiving treatment for sickle cell disease (such as voxelotor, crizanlizumab, or L-glutamine), with the exception of hydroxyurea
  • If you're currently receiving therapies that stimulate blood production, such as erythropoietin

Having higher participation in clinical trials helps give clarity on the options and opportunities available to us. It's beneficial for the greater good.


Sickle Cell Warrior